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Gene Expression Data
Assay Details
Assay
Reference: J:287563 Mercader N, et al., Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner. Int J Dev Biol. 2009;53(8-10):1483-94
Assay type: RNA in situ
MGI Accession ID: MGI:6436617
Gene symbol: Meis1
Gene name: Meis homeobox 1
Probe: Meis1a probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 9.5 (more )
Note: 22 somite-stage embryo
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 1A A distal domain lacking expression is detected.
Specimen 1B: embryonic day 9.5 (more )
Note: 23 somite-stage embryo
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 1B A distal domain lacking expression is detected.
Specimen 1C: embryonic day 9.5 (more )
Note: 28 somite-stage embryo
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 1C A distal domain lacking expression is detected.
Specimen 1D: embryonic day 10.0 (more )
Note: 33 somite-stage embryo
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 1D A distal domain lacking expression is detected.
Specimen 1E: embryonic day 11.0 (more )
Note: 44 somite-stage embryo
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 1E A distal domain lacking expression is detected.
Specimen 1F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: arm Present Regionally restricted 1F Expression is restricted to the proximal-most limb region.
TS20: forelimb pre-cartilage condensation Absent 1F
Specimen 2A: embryonic day 10.0 (more )
Note: 34 somite-stage embryo; section through the posterior limb
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 2A Expression is excluded from a distal domain.
Specimen 2B: embryonic day 10.0 (more )
Note: 34 somite-stage embryo; section through the medial limb
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 2B Expression is excluded from a distal domain.
Specimen 2C: embryonic day 10.0 (more )
Note: 34 somite-stage embryo; section through the anterior limb
Structure Level Pattern Image Note
TS16: forelimb bud mesenchyme Present Regionally restricted 2C Expression is excluded from a distal domain.
Specimen 3A: embryonic day 9.75 (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Present Regionally restricted 3A Expression is excluded from a distal domain.
Specimen 3B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present 3B
Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: arm Present 3C Expression is restricted to the proximal-most limb region.
Specimen 3D: embryonic day 11.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS19: future arm mesenchyme Present 3D
TS19: handplate apical ectodermal ridge Absent 3D
Specimen 8A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 8A Expression is seen in a proximal domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory