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Gene Expression Data
Assay Details
Assay
Reference: J:286739 Wazin F, et al., The negative regulatory Spred1 and Spred2 proteins are required for lens and eye morphogenesis. Exp Eye Res. 2020 Feb;191:107917
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6436343
Gene symbol: Mapk1
Gene name: mitogen-activated protein kinase 1
Antibody: anti-phospho-Erk1/2
Detection system: Secondary antibody
Assay notes: The antibody used in this assay recognizes the phosphorylated form of the protein.
Results
Specimen 1E: embryonic day 13.5; Spred1tm1Hiin/Spred1+, Spred2tm1Taga/Spred2+ (more )
Note: Littermate control.
Structure Level Pattern Image Note
TS21: lens epithelium Present 1E
Specimen 1F: embryonic day 13.5; Spred1tm1Hiin/Spred1tm1Hiin, Spred2tm1Taga/Spred2tm1Taga (more )
Structure Level Pattern Image Note
TS21: lens epithelium Present 1F Expression in the mutant is increased relative to wild type, in particular in the germinative and transitional regions.
TS21: eye Present Widespread 1F Expression is increased throughout the lens, including the surrounding ocular tissues.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory