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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6434459
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti Pax2 Z-RX2 (71-6000)
Detection system: Biotinylated secondary antibody/[Strept]avidin
Results
Specimen 4M: embryonic day 9.75; Smotm2Amc/Smo+ (more )
Note: 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present 4M
Specimen 4N: embryonic day 9.75; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present 4N
Specimen 4O: embryonic day 9.75; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 27 somites
Structure Level Pattern Image Note
TS15: optic cup Present 4O Expression not obviously different among all genotypes.
Specimen 4P: embryonic day 10.25; Smotm2Amc/Smo+ (more )
Note: 32 somites
Structure Level Pattern Image Note
TS16: optic cup Present 4P
TS16: optic stalk Present 4P
Specimen 4Q: embryonic day 10.25; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 32 somites
Structure Level Pattern Image Note
TS16: optic cup Present 4Q
TS16: optic stalk Present 4Q
Specimen 4R: embryonic day 10.25; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 32 somites
Structure Level Pattern Image Note
TS16: optic cup Absent 4R No expression in dorsal optic cup.
TS16: optic stalk Present 4R Expression domain in optic stalk similar to that of controls.
Specimen 4S: embryonic day 11.0; Smotm2Amc/Smo+ (more )
Note: 40 somites
Structure Level Pattern Image Note
TS17: optic cup Present 4S
TS17: optic stalk Present 4S
Specimen 4T: embryonic day 11.0; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 40 somites
Structure Level Pattern Image Note
TS17: optic cup Present 4T
TS17: optic stalk Present 4T
Specimen 4U: embryonic day 11.0; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 40 somites
Structure Level Pattern Image Note
TS17: optic cup Weak 4U Expression reduced compared to controls in both optic cup and optic stalk.
TS17: optic stalk Weak 4U Expression reduced compared to controls in both optic cup and optic stalk.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory