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Gene Expression Data
Assay Details
Assay
Reference: J:156737 Zhao L, et al., Sonic hedgehog is involved in formation of the ventral optic cup by limiting Bmp4 expression to the dorsal domain. Mech Dev. 2010 January - February;127(1-2):62-72
Assay type: RNA in situ
MGI Accession ID: MGI:6434447
Gene symbol: Smo
Gene name: smoothened, frizzled class receptor
Probe: Smo probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1G: embryonic day 9.5; Smotm2Amc/Smo+ (more )
Note: 20 somites
Structure Level Pattern Image Note
TS15: optic stalk Present 1G
TS15: optic vesicle Present 1G
Specimen 1H: embryonic day 9.5; Smotm2Amc/Smo+, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS15: optic stalk Present 1H
TS15: optic vesicle Present 1H
Specimen 1I: embryonic day 9.5; Smotm1Amc/Smotm2Amc, Tg(Fgf15-cre)1Hisa/0 (more )
Note: Conditional mutant. 20 somites
Structure Level Pattern Image Note
TS15: optic stalk Absent 1I Expression completely abolished in optic vesicle and optic stalk.
TS15: optic vesicle Absent 1I Expression completely abolished in optic vesicle and optic stalk.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory