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Gene Expression Data
Assay Details
Assay
Reference: J:98484 Lickert H, et al., Dissecting Wnt/{beta}-catenin signaling during gastrulation using RNA interference in mouse embryos. Development. 2005 Jun;132(11):2599-609
Assay type: RNA in situ
MGI Accession ID: MGI:6432905
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Probe: IMAGE clone 5707193
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2I wt: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem (more )
Structure Level Pattern Image Note
TS11: chorion Present 2I wt
TS11: embryo Present Regionally restricted 2I wt Expression in anterior epiblast.

Specimen 2I CKO: embryonic day 7.5; Ctnnb1tm2Kem/Ctnnb1tm2.1Kem, Krt19tm1(cre)Mmt/Krt19+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS11: chorion Present 2I CKO Extraembryonic expression unaffected in mutant.
TS11: embryo Present Widespread 2I CKO Expression in whole epiblast.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory