Gbx2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:98484 Lickert H, et al., Dissecting Wnt/{beta}-catenin signaling during gastrulation using RNA interference in mouse embryos. Development. 2005 Jun;132(11):2599-609
Assay type:	RNA in situ
MGI Accession ID:	MGI:6432903
Gene symbol:	Gbx2
Gene name:	gastrulation brain homeobox 2

Probe:	Gbx2 cDNA2
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

2G wt ©

Specimen 2G wt: embryonic day 7.5; Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem (more

)

Structure	Level	Pattern	Image	Note
TS11: primitive streak	Present		2G wt

2G CKO ©

Specimen 2G CKO: embryonic day 7.5; Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem, Krt19^tm1(cre)Mmt/Krt19⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS11: primitive streak	Weak		2G CKO	Expression dowregulated in mutant.

5G wt ©

Specimen 5G wt: embryonic day 8.0; Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem (more

)
Note: 7-8 somite stage.

Structure	Level	Pattern	Image	Note
TS13: rhombomere 1	Present		5G wt
TS13: rhombomere 2	Present		5G wt
TS13: embryo	Present	Regionally restricted	5G wt	Expression in tailbud.

5I wt A ©

Specimen 5I wt A: embryonic day 7.5; Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem (more

)
Note: Headfold stage.

Structure	Level	Pattern	Image	Note
TS11: embryo	Present	Regionally restricted	5I wt A	Expression in epiblast.

5I wt P ©

Specimen 5I wt P: embryonic day 7.5; Ctnnb1^tm2Kem/Ctnnb1^tm2.1Kem (more

)
Note: Headfold stage.

Structure	Level	Pattern	Image	Note
TS11: embryo	Present	Regionally restricted	5I wt P	Expression in epiblast.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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