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Gene Expression Data
Assay Details
Assay
Reference: J:285850 Qian C, et al., Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice. Cell Death Differ. 2019 Aug;26(8):1396-1410
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430379
Gene symbol: Pdgfra
Gene name: platelet derived growth factor receptor, alpha polypeptide
Antibody: anti-Pdgfra (ab124392)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1 - E10.5: embryonic day 10.5 (more )
Note: transverse section
Structure Level Pattern Image Note
TS17: cloaca associated mesenchyme Present 1_E10.5 Labeling is localized in the mesenchyme surrounding the cloaca.
Specimen 1 - E11.5-12: embryonic day 11.5-12.0 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS19: genital tubercle Present Widespread 1_E11.5-12
TS19: hindgut mesenchyme Present Widespread 1_E11.5-12
TS19: urorectal septum Present Widespread 1_E11.5-12
Specimen 1 - E12.5: embryonic day 12.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS20: cloacal membrane Present 1_E12.5
TS20: genital tubercle mesenchyme Present 1_E12.5
TS20: hindgut mesenchyme Present 1_E12.5
TS20: urorectal septum Present 1_E12.5
Specimen 1 - E13.5: embryonic day 13.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS21: genital tubercle Present 1_E13.5
TS21: hindgut mesenchyme Present 1_E13.5
TS21: urorectal septum Present 1_E13.5 Labeling is localized in the mesenchyme.
TS21: mesenchyme of urogenital sinus Present 1_E13.5 Labeling is localized in the mesenchyme surrounding the cloaca membrane and the urogenital sinus.
Specimen 1 - E14.5: embryonic day 14.5 (more )
Note: sagittal section
Structure Level Pattern Image Note
TS22: urinary system mesenchyme Present 1_E14.5 Expression is localized in the mesenchyme adjacent to the ureter and urethra.
TS22: urorectal septum Present 1_E14.5
TS22: urethral plate epithelium Present 1_E14.5 Expression is localized in the urethral plate mesenchyme.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory