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Gene Expression Data
Assay Details
Assay
Reference: J:272566 Yang R, et al., CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6423308
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated Caspase 3 (AF835)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 5F: postnatal month 1 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: liver Absent 5F
Specimen 5F': postnatal month 1; Cdk5rap3tm1c(EUCOMM)Hmgu/Cdk5rap3tm1c(EUCOMM)Hmgu, Tg(Foxa3-cre)1Khk/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: liver Absent 5F' No obvious apoptosis was detected in the conditional knockout livers at 1 month.
Specimen S3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: liver Trace S3D Expression was rarely detected in wild type at E14.5.
Specimen S3D': embryonic day 14.5; Cdk5rap3tm1b(EUCOMM)Hmgu/Cdk5rap3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS22: liver Trace S3D' Expression was rarely detected in the knockout at E14.5.
Specimen S3E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: liver Trace S3E Few apoptotic cells were detected in wild type at E16.5.
Specimen S3E': embryonic day 16.5; Cdk5rap3tm1b(EUCOMM)Hmgu/Cdk5rap3tm1b(EUCOMM)Hmgu (more )
Structure Level Pattern Image Note
TS24: liver Present S3E' Many apoptotic cells were observed in knockout livers at E16.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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