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Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416329
Gene symbol: Bcl11b
Gene name: B cell leukemia/lymphoma 11B
Results
Specimen 4K: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Triple labeled: blue - Bcl11b; green - Eomes (assay MGI:6416157); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: telencephalon Present 4K

Specimen 4L: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Triple labeled: blue - Bcl11b; green - Eomes (assay MGI:6416157); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: telencephalon Present 4L

Specimen S6A: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Triple labeled: blue - Bcl11b; green - Eomes (assay MGI:6416157); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted S6A Expression was detected in deep layer cortical neurons.

Specimen S6B: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Triple labeled: blue - Bcl11b; green - Eomes (assay MGI:6416157); red - Sox2 (assay MGI:6416328).
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted S6B The number of Bcl11b-immunopositive neurons was not affected by the conditional mutation.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory