About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:242313 Forge A, et al., Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear. PLoS Genet. 2017 Mar;13(3):e1006692
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6414888
Gene symbol: Prkcz
Gene name: protein kinase C, zeta
Antibody: Anti-PKC zeta (sc-216; C-20)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 11E normal: postnatal day 1 (more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 11E' , 11E Expression localised to the apical surface of the outer and inner hair cells, specifically on the medial side.
Specimen 11F affected: postnatal day 1; Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa (more )
Note: Double labeled: green - aPKC; red - actin
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 11F' , 11F Expression is seen at the surface of hair cells, but the distribution is symmetric around the entire circumference and across their apical surface, not asymmetric as is seen in normal animals.
Specimen 12E normal: postnatal day 1 (more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted 12E' , 12E Expression is detected at the surface of hair cells, most strongly on the medial side.
Specimen 12F affected: postnatal day 1; Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa (more )
Note: Double labeled: green - aPKC; red - actin
Structure Level Pattern Image Note
TS27: macula of utricle Present Regionally restricted 12F , 12F' Expression is seen at the surface of hair cells, but the distribution is symmetric around the entire circumference and across their apical surface, not asymmetric as is seen in normal animals.
Specimen 13E normal: postnatal day 1 (more )
Note: Littermate control; mouse might carry the Cre transgene. Double labeled: green - aPKC; red - actin.
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted 13E' , 13E Expression is seen at the surface of hair cells, most strongly on the medial side.
Specimen 13F affected: postnatal day 1; Tg(Tek-cre)1Ywa/Tg(Tek-cre)1Ywa (more )
Note: Double labeled: green - aPKC; red - actin
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted 13F , 13F' Expression is seen at the surface of hair cells, but the distribution is symmetric, not asymmetric as is seen in normal animals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory