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Gene Expression Data
Assay Details
Assay
Reference: J:138147 Gros-Louis F, et al., Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish. Hum Mol Genet. 2008 Sep 1;17(17):2691-702
Assay type: Western blot
MGI Accession ID: MGI:6414768
Gene symbol: Tubb3
Gene name: tubulin, beta 3 class III
Antibody: anti-beta-tubulin
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 3A
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
+/+ 478 days P478 TS28: sciatic nerve Present C57BL/6 Not Specified
+/- 478 days P478 TS28: sciatic nerve Present either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Als2tm1Garo/Als2+Not Specified
-/- 130 days P130 TS28: sciatic nerve Strong either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Als2tm1Garo/Als2tm1GaroNot Specified
-/- 320 days P320 TS28: sciatic nerve Strong either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Als2tm1Garo/Als2tm1GaroNot Specified
-/- 478 days P478 TS28: sciatic nerve Strong (a) either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6) Als2tm1Garo/Als2tm1GaroNot Specified
Notes:
(a) Levels increased with age in the mutant animals.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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