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Gene Expression Data
Assay Details
Assay
Reference: J:149502 Hill P, et al., A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud. Dev Biol. 2009 Apr 15;328(2):506-16
Assay type: RNA in situ
MGI Accession ID: MGI:6404096
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe102
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Widespread 3D Expression in entire apical ectodermal ridge. Expression decreased in anterior-most part of limb bud.

Specimen 3E: embryonic day 11.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong Regionally restricted 3E Increased expression, with anterior expansion of expression up to presumptive border of zeugo- and autopod (ie. the wrist region).

Specimen 3F: embryonic day 11.5; Gli3tm1Urt/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong Regionally restricted 3F Expression more intense than in wild type litermates, but no anterior expansion.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory