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Gene Expression Data
Assay Details
Assay
Reference: J:146434 Maatouk DM, et al., In the limb AER Bmp2 and Bmp4 are required for dorsal-ventral patterning and interdigital cell death but not limb outgrowth. Dev Biol. 2009 Mar 15;327(2):516-23
Assay type: RNA in situ
MGI Accession ID: MGI:6403984
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Results
Specimen 1C: embryonic day 10.5; Bmp2tm1Cjt/Bmp2tm1Cjt, Bmp4tm1Jfm/Bmp4tm1Jfm (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present Widespread 1C Expression throughout apical ectodermal ridge.
TS17: hindlimb bud mesenchyme Present Regionally restricted 1C Expression in posterior mesenchyme.
Specimen 1D: embryonic day 10.5; Bmp2tm1Cjt/Bmp2tm1Cjt, Bmp4tm1Jfm/Bmp4tm1Jfm, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Absent 1D
Specimen E10.5 forelimb bud not specified: embryonic day 10.5; Bmp2tm1Cjt/Bmp2tm1Cjt, Bmp4tm1Jfm/Bmp4tm1Jfm, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Ambiguous Patchy
Specimen S3C: embryonic day 13.5; Bmp2tm1Cjt/Bmp2tm1Cjt, Bmp4tm1Jfm/Bmp4tm1Jfm (more )
Structure Level Pattern Image Note
TS21: hindlimb interdigital region Present S3C
Specimen S3D: embryonic day 13.5; Bmp2tm1Cjt/Bmp2tm1Cjt, Bmp4tm1Jfm/Bmp4tm1Jfm, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: hindlimb interdigital region Present S3D Expression not altered compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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