About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:284140 Frum T, et al., TEAD4, YAP1 and WWTR1 prevent the premature onset of pluripotency prior to the 16-cell stage. Development. 2019 Sep 6;146(17):dev179861
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6403726
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-uvomorulin/E-Cadherin (DECMA-1), rat
Detection system: Secondary antibody
Results
Specimen 1A non-mutant: embryonic day 3.0 (more )
Note: 16-cell stage. This embryo was the result of a cross between double heterozygotes. It displays a wild-type staining pattern. It may carry no mutant alleles or it may be heterozygous for either or both Nanog and Pou5f1 (Oct4).
Structure Level Pattern Image Note
TS3: compacted morula Present Regionally restricted 1A ECAD upper This staining was used to distinguish between inside and outside cells.

Specimen 1A Nanog; Oct4 null: embryonic day 3.0; Nanogtm1Hoch/Nanogtm1Hoch, Pou5f1tm1.1Scho/Pou5f1tm1.1Scho (more )
Note: 16-cell stage.
Structure Level Pattern Image Note
TS3: compacted morula Present Regionally restricted 1A ECAD lower This staining was used to distinguish between inside and outside cells.

Specimen 1B non-mutant: embryonic day 3.25 (more )
Note: 32-cell stage. This embryo was the result of a cross between double heterozygotes. It displays a wild-type staining pattern. It may carry no mutant alleles or it may be heterozygous for either or both Nanog and Pou5f1 (Oct4).
Structure Level Pattern Image Note
TS3: compacted morula Present Regionally restricted 1B ECAD upper This staining was used to distinguish between inside and outside cells.

Specimen 1B Nanog; Oct4 null: embryonic day 3.25; Nanogtm1Hoch/Nanogtm1Hoch, Pou5f1tm1.1Scho/Pou5f1tm1.1Scho (more )
Note: 32-cell stage.
Structure Level Pattern Image Note
TS3: compacted morula Present Regionally restricted 1B ECAD lower This staining was used to distinguish between inside and outside cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory