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Gene Expression Data
Assay Details
Assay
Reference: J:233748 Yzaguirre AD, et al., Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos. Dev Biol. 2016 Jul 1;415(1):111-21
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6400720
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen 2A: embryonic day 10.5 (more )
Note: Double labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721).
Structure Level Pattern Image Note
TS17: dorsal aorta Present 2A
TS17: umbilical artery Present 2A
TS17: vitelline artery Present 2A
TS17: hematopoietic system Present Regionally restricted 2A Expression in extravascular islands in region between vitelline and umbilical arteries in the embryo proper.
Specimen 2Ai/ii: embryonic day 10.5 (more )
Note: Double labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721).
Structure Level Pattern Image Note
TS17: umbilical artery Present 2Aii , 2Ai
TS17: vitelline artery Present 2Aii , 2Ai
TS17: hematopoietic system Present Regionally restricted 2Ai , 2Aii Expression in extravascular islands in region between vitelline and umbilical arteries in the embryo proper.
Specimen 4Ai/ii: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: vitelline artery Present 4Aii , 4Ai
TS17: yolk sac blood vessel Present 4Aii , 4Ai
TS17: hematopoietic system Present Regionally restricted 4Ai , 4Aii Expression in a large type III extravascular island between vitelline artery and vascular plexus.
Specimen 4Bi: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: vitelline artery Present 4Bi
TS17: hematopoietic system Present Regionally restricted 4Bi Expression in a large type III extravascular island between vitelline artery and vascular plexus.
Specimen 4Ci: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 4Ci Expression in a large type III extravascular island between vitelline artery and vascular plexus.
Specimen 4Fi: embryonic day 11.5 (more )
Note: 46 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS19: umbilical artery Present 4Fi
TS19: hematopoietic system Present Regionally restricted 4Fi Expression in a type III extravascular island at base of umbilical artery where it connects to the placenta.
Specimen 4Fi inset: embryonic day 11.5 (more )
Note: 46 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS19: hematopoietic system Present Regionally restricted 4Fi inset Expression in a type III extravascular island at base of umbilical artery where it connects to the placenta.
Specimen 5Ai: embryonic day 10.0 (more )
Note: 34 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS16: dorsal aorta Present 5Ai
TS16: vitelline artery Present 5Ai
TS16: trunk blood vessel Present Regionally restricted 5Ai Expression in tributary vessels connecting dorsal aorta and vitelline artery.
TS16: hematopoietic system Present Regionally restricted 5Ai Expression in hematopoietic clusters.
Specimen 5Bi: embryonic day 10.0 (more )
Note: 32 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS16: vitelline artery Present 5Bi
TS16: trunk blood vessel Present Regionally restricted 5Bi Expression in tributary vessels connecting dorsal aorta and vitelline artery.
TS16: hematopoietic system Present Regionally restricted 5Bi Expression in hematopoietic clusters.
Specimen 6A Umbilical Artery: embryonic day 10.5 (more )
Note: 34-36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: umbilical artery Present Regionally restricted 6Aii (top) , 6Ai (top) Expression in endothelial cells egressing away from lument of umbilical artery as hematopoietic cluster is extruded.
TS17: hematopoietic system Present Regionally restricted 6Ai (top) , 6Aii (top) Expression in hematopoietic clusters.
Specimen 6A Dorsal Aorta: embryonic day 10.5 (more )
Note: 34-36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: dorsal aorta Present Regionally restricted 6Aii (bottom) , 6Ai (bottom) Authors report no ballooning of endothelium benearth hematopoietic clusters in the dorsal aorta.
TS17: hematopoietic system Present Regionally restricted 6Ai (bottom) , 6Aii (bottom) Expression in hematopoietic clusters.
Specimen E11.5 not shown: embryonic day 11.5 (more )
Note: 42-49 somite pairs.
Structure Level Pattern Image Note
TS19: dorsal aorta Present Regionally restricted Authors report no ballooning of endothelium beneath hematopoietic clusters in the dorsal aorta.
TS19: hematopoietic system Present Regionally restricted Expression in hematopoietic clusters.
Specimen 6B: embryonic day 10.0 (more )
Note: 32 somite pairs.
Structure Level Pattern Image Note
TS16: dorsal aorta Present 6B
TS16: umbilical artery Present 6B
TS16: vitelline artery Present Regionally restricted 6B Authors report ballooning of the vitelline artery. Expression in balloon-shaped extrusion of endothelial cells that has entrapped part of a hematopoietic cluster.
Specimen 6C: embryonic day 10.0 (more )
Note: 32 somite pairs.
Structure Level Pattern Image Note
TS16: vitelline artery Present 6C
TS16: hematopoietic system Present Regionally restricted 6C Expression in hematopoietic cluster, partly entrapped by endothelial cells, the rest intra-arterial.
Specimen 8D: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); white - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: umbilical artery Present 8D
TS17: hematopoietic system Present Regionally restricted 8D Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery.
Specimen 8E: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); white - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8E Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery.
Specimen 8F: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); white - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: hematopoietic system Present Regionally restricted 8F Expression in large elongated type II, III and IV extravascular islands on cranial side of umbilical artery.
Specimen 8J: embryonic day 10.0 (more )
Note: 32 somite pairs. Triple labeled: red - CD31 (Pecam1); white - Runx1 (assay MGI:6400721); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS16: umbilical artery Present 8J
TS16: blood vessel Present Regionally restricted 8J Expression in well-developed small diameter vessels running parallel to umbilical vessels.
TS16: hematopoietic system Present Regionally restricted 8J Expression in a cluster of hematopoietic cells connected to the small vessel.
Specimen 9Ai: embryonic day 10.5 (more )
Note: 32-36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Prox1 (assay MGI:6400723); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: cardinal vein Present 9Ai
TS17: intersomitic blood vessel Present 9Ai
Specimen 9Bi: embryonic day 10.5 (more )
Note: 32-36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Prox1 (assay MGI:6400723); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: vitelline artery Present 9Bi
TS17: hematopoietic system Present Regionally restricted 9Bi Expression in a small type I extravascular island near the vitelline artery.
Specimen 9Di: embryonic day 10.5 (more )
Note: 36 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Prox1 (assay MGI:6400723); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: umbilical artery Present 9Di
TS17: hematopoietic system Present Regionally restricted 9Di Expression in type II extravascular island near the umbilical artery.
Specimen 9Fi: embryonic day 10.5 (more )
Note: 38 somite pairs. Triple labeled: red - CD31 (Pecam1); green - Prox1 (assay MGI:6400723); blue - Kit (assay MGI:6400722).
Structure Level Pattern Image Note
TS17: vitelline artery Present 9Fi
TS17: yolk sac blood vessel Present 9Fi
TS17: hematopoietic system Present Regionally restricted 9Fi Expression in type II extravascular island near vitelline artery in yolk sac.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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