Gene Expression Data
Assay Details
Assay
|
Reference:
|
J:233609
Van Otterloo E, et al., MEMO1 drives cranial endochondral ossification and palatogenesis. Dev Biol. 2016 Jul 15;415(2):278-95
|
Assay type:
|
In situ reporter (knock in)
|
MGI Accession ID:
|
MGI:6400513
|
Gene symbol:
|
Memo1
|
Gene name:
|
mediator of cell motility 1
|
Reporter:
|
lacZ
|
|
Direct Detection
|
|
Results
|
Specimen
4D:
embryonic day 13.5; Memo1tm1a(EUCOMM)Wtsi/Memo1 +
(more )
Note: Single palatal shelf prior to palatal fusion.
Specimen
4D:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Single palatal shelf prior to palatal fusion.
|
Specimen
4E:
embryonic day 15.5; Memo1tm1a(EUCOMM)Wtsi/Memo1 +
(more )
Note: Subsequent to secondary palatal fusion. Frontal section slightly more posterior than section shown in 4F.
Specimen
4E:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Subsequent to secondary palatal fusion. Frontal section slightly more posterior than section shown in 4F.
|
Specimen
4F:
embryonic day 15.5; Memo1tm1a(EUCOMM)Wtsi/Memo1 +
(more )
Note: Subsequent to secondary palatal fusion
Specimen
4F:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Subsequent to secondary palatal fusion
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: palatal shelf |
Present |
Regionally restricted |
4F
|
Expression reduced at midline of palate; enriched expression at periphery near developing maxillary bones.
|
TS23: nasal septum epithelium |
Weak |
|
4F
|
Far less prominent expression in ectoderm of palatal shelves or nasal septum.
|
TS23: palatal shelf epithelium |
Weak |
|
4F
|
Far less prominent expression in ectoderm of palatal shelves or nasal septum.
|
Specimen
4G:
embryonic day 15.5; Memo1tm1a(EUCOMM)Wtsi/Memo1 +
(more )
Note: Mid-sagittal section of entire head.
Specimen
4G:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Mid-sagittal section of entire head.
|
Specimen
4H:
embryonic day 15.5; Memo1tm1a(EUCOMM)Wtsi/Memo1 +
(more )
Note: Secondary palate and anterior cranial base.
Specimen
4H:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Secondary palate and anterior cranial base.
|
Specimen
4I:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Mid-cranial base.
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: basisphenoid bone |
Strong |
Regionally restricted |
4I
|
Strong expression in perichondrium. Lower levels of expression in cells at various stages of chondrocyte differentiation.
|
TS23: cranium |
Present |
Regionally restricted |
4I
|
Expression within developing cranial base bones.
|
TS23: pituitary gland |
Present |
|
4I
|
|
Specimen
4J:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Posterior cranial base.
|
Structure |
Level |
Pattern |
Image |
Note |
TS23: basioccipital bone |
Strong |
Regionally restricted |
4J
|
Strong expression in periosteum.
|
TS23: cranium |
Present |
Regionally restricted |
4J
|
Expression within developing cranial base bones.
|
Specimen
4K:
(close )
Genetic Background:
|
involves: Black Swiss * C57BL/6
|
Mutant Allele(s):
|
Memo1tm1a(EUCOMM)Wtsi/Memo1+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Note:
|
Snout.
|
|