Ptch1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:160585 Kesper DA, et al., Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
Assay type:	RNA in situ
MGI Accession ID:	MGI:6394024
Gene symbol:	Ptch1
Gene name:	patched 1

Probe:	M2-3
Probe preparation:	Antisense labelled with P33 RNA

Results

1Q ©

Specimen 1Q: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Present	Regionally restricted	1Q	Expression is in proliferating chondrocytes flanking the hypertrophic region.

1R ©

Specimen 1R: embryonic day 16.5; Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Absent		1R

1S ©

Specimen 1S: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Ihh^tm1Amc/Ihh^tm1Amc, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb skin	Present		1S
TS24: forelimb cartilage condensation	Absent		1S

1T ©

Specimen 1T: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Ihh^tm1Amc/Ihh^tm1Amc, Tg(COL2A1-cre)1Wag/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb skin	Present		1T
TS24: forelimb cartilage condensation	Absent		1T

2M ©

Specimen 2M: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Strong	Regionally restricted	2M	Expression is in proliferating chondrocytes flanking the hypertrophic region.
TS24: perichondrium	Strong		2M

2N ©

Specimen 2N: embryonic day 16.5; Gli3^Xt-J/Gli3^Xt-J, Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Weak	Regionally restricted	2N	Expression is in chondrocytes.

2O ©

Specimen 2O: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Gli3^Xt-J/Gli3^Xt-J, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Weak	Regionally restricted	2O	Expression is in chondrocytes.
TS24: perichondrium	Absent		2O

2P ©

Specimen 2P: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Gli3^Xt-J/Gli3^Xt-J, Tg(COL2A1-cre)1Wag/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Weak	Regionally restricted	2P	Expression is in chondrocytes.
TS24: perichondrium	Strong		2P

3G ©

Specimen 3G: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Strong		3G

3H ©

Specimen 3H: embryonic day 16.5; Gli3^Xt-J/Gli3^Xt-J (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Strong		3H

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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