Gli1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:160585 Kesper DA, et al., Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26
Assay type:	RNA in situ
MGI Accession ID:	MGI:6394023
Gene symbol:	Gli1
Gene name:	GLI-Kruppel family member GLI1

Probe:	Gli cDNA3
Probe preparation:	Antisense labelled with P33 RNA

Results

1M ©

Specimen 1M: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Present	Regionally restricted	1M	Expression is in proliferating chondrocytes flanking the hypertrophic region.

1N ©

Specimen 1N: embryonic day 16.5; Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Absent		1N

1O ©

Specimen 1O: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Ihh^tm1Amc/Ihh^tm1Amc, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb skin	Present		1O
TS24: forelimb cartilage condensation	Absent		1O

1P ©

Specimen 1P: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Ihh^tm1Amc/Ihh^tm1Amc, Tg(COL2A1-cre)1Wag/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb skin	Present		1P
TS24: forelimb cartilage condensation	Absent		1P

2I ©

Specimen 2I: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Present	Regionally restricted	2I	Expression is in proliferating chondrocytes flanking the hypertrophic region.

2J ©

Specimen 2J: embryonic day 16.5; Gli3^Xt-J/Gli3^Xt-J, Ihh^tm1Amc/Ihh^tm1Amc (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Absent		2J	Expression is absent in the skeletal elements.

2K ©

Specimen 2K: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Gli3^Xt-J/Gli3^Xt-J, Tg(Prrx1-cre)1Cjt/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb mesenchyme	Absent		2K

2L ©

Specimen 2L: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj, Gli3^Xt-J/Gli3^Xt-J, Tg(COL2A1-cre)1Wag/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Absent		2L

3E ©

Specimen 3E: embryonic day 16.5; Gli2^tm6Alj/Gli2^tm6Alj (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Present		3E

3F ©

Specimen 3F: embryonic day 16.5; Gli3^Xt-J/Gli3^Xt-J (more

)

Structure	Level	Pattern	Image	Note
TS24: forelimb cartilage condensation	Present		3F

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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