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Gene Expression Data
Assay Details
Assay
Reference: J:86321 Shibata S, et al., In situ hybridization and immunohistochemistry of versican, aggrecan and link protein, and histochemistry of hyaluronan in the developing mouse limb bud cartilage. J Anat. 2003 Oct;203(4):425-32
Assay type: RNA in situ
MGI Accession ID: MGI:6393923
Gene symbol: Hapln1
Gene name: hyaluronan and proteoglycan link protein 1
Probe: Link protein cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen not shown: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: hindlimb digit cartilage condensation Absent
Specimen 2d: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present 2d Expression was detected throughout the tibial cartilage.
Specimen 3c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tibia cartilage condensation Present 3c Expression was similar to that of Aggrecan, which was detected in chondrocytes of the metaphysis and the epiphysis but reduced in the hypertrophic chondrocytes of the diaphysis.
Specimen 4c: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: tibia Strong Non-Uniform 4c Strong expression was detected in the chondrocytes of the metaphysis. Weak expression was detected in chondrocytes of the epiphysis, but not detected in the hypertrophic chondrocytes of the diaphysis. Expression in the epiphysis was stronger in chondrocytes of the marginal area.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory