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Gene Expression Data
Assay Details
Assay
Reference: J:285046 Law S, et al., Expression of MYOSIN VIIA in developing mouse cochleovestibular ganglion neurons. Gene Expr Patterns. 2020 Jan 7;35:119092
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6393615
Gene symbol: Myo7a
Gene name: myosin VIIA
Antibody: anti-myosin VIIa (#25-6790)
Detection system: Alexa Fluor 488
Results
Specimen 4B/C: embryonic day 10.5 (more )
Note: Double labeled: green - Myo7a; red - Neurod1 (assay MGI:6393618).
Structure Level Pattern Image Note
TS17: acoustic ganglion Present Regionally restricted 4B , 4C Cytoplasmic expression in ncuroblasts in cochleovestibular ganglion.
TS17: otocyst epithelium Ambiguous Regionally restricted 4B , 4C No expression in neuroblasts in otic epithelium.

Specimen 4C inset: embryonic day 10.5 (more )
Note: Double labeled: green - Myo7a; red - Neurod1 (assay MGI:6393618).
Structure Level Pattern Image Note
TS17: acoustic ganglion Present Regionally restricted 4C inset Co-expression with Neurod1 in cochleovestibular ganglion.

Specimen 4E/F: embryonic day 11.5 (more )
Note: Double labeled: green - Myo7a; red - Neurod1 (assay MGI:6393618).
Structure Level Pattern Image Note
TS19: acoustic ganglion Present Regionally restricted 4E , 4F Cytoplasmic expression in subset of neurons at outer edge of cochleovestibular ganglion. Expression downregulated in postmitotic cells not expressing Neurod1.

Specimen 4F inset: embryonic day 11.5 (more )
Note: Double labeled: green - Myo7a; red - Neurod1 (assay MGI:6393618).
Structure Level Pattern Image Note
TS19: acoustic ganglion Present Regionally restricted 4F inset Co-expression with Neurod1 in subset of Neurod1-expressing cells in cochleovestibular ganglion.

Specimen 5B/C: embryonic day 10.5 (more )
Note: Double labeled: green - Myo7a; red - Gata3 (assay MGI:6393619).
Structure Level Pattern Image Note
TS17: acoustic ganglion Present Regionally restricted 5B , 5C Cytoplasmic expression in cochleovestibular ganglion.
TS17: otocyst epithelium Present Regionally restricted 5B , 5C Based on morphology, expressing cells likely to be presumptive hair cells. Expression in a few delaminating neurons adjacent to otic epithelium.

Specimen 5C inset: embryonic day 10.5 (more )
Note: Double labeled: green - Myo7a; red - Gata3 (assay MGI:6393619).
Structure Level Pattern Image Note
TS17: acoustic ganglion Present Regionally restricted 5C inset Co-expression with Gata3 in cochleovestibular ganglion

Specimen 5E/F: embryonic day 11.5 (more )
Note: Double labeled: green - Myo7a; red - Gata3 (assay MGI:6393619).
Structure Level Pattern Image Note
TS19: acoustic ganglion Present Regionally restricted 5F , 5E Cytoplasmic expression in subset of neurons at outer edge of cochleovestibular ganglion.

Specimen 5F inset: embryonic day 11.5 (more )
Note: Double labeled: green - Myo7a; red - Gata3 (assay MGI:6393619).
Structure Level Pattern Image Note
TS19: acoustic ganglion Present Regionally restricted 5F inset No co-expression with Gata3.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory