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Gene Expression Data
Assay Details
Assay
Reference: J:228519 Jia S, et al., Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1. Dev Biol. 2015 Dec 1;408(1):90-8
Assay type: RNA in situ
MGI Accession ID: MGI:6391196
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Probe: Ascl1 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3D +/lacZ: embryonic day 13.5; Insm1tm1Cbm/Insm1+ (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present 3D +/lacZ
Specimen 3D lacZ/lacZ: embryonic day 13.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Structure Level Pattern Image Note
TS21: lung epithelium Present Regionally restricted 3D lacZ/lacZ Expression pattern comparable to that of control embryos.
Specimen 3E +/lacZ: embryonic day 15.5; Insm1tm1Cbm/Insm1+ (more )
Structure Level Pattern Image Note
TS23: lung epithelium Present 3E +/lacZ
Specimen 3E lacZ/lacZ: embryonic day 15.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Structure Level Pattern Image Note
TS23: lung epithelium Weak 3E lacZ/lacZ Reduced expression levels at E15.5
Specimen 3F +/lacZ: embryonic day 18.5; Insm1tm1Cbm/Insm1+ (more )
Structure Level Pattern Image Note
TS26: lung epithelium Present 3F +/lacZ
Specimen 3F lacZ/lacZ: embryonic day 18.5; Insm1tm1Cbm/Insm1tm1Cbm (more )
Structure Level Pattern Image Note
TS26: lung epithelium Absent 3F lacZ/lacZ Expression not detectable at E18.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory