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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6391105
Gene symbol: Nefm
Gene name: neurofilament, medium polypeptide
Results
Specimen E11.5 WT not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: peripheral nerve Present Regionally restricted Expression in peripheral nerves.
Specimen 5B WT: embryonic day 12.25 (more )
Structure Level Pattern Image Note
TS20: peripheral nerve Present Regionally restricted 5B WT Expression in developing peripheral nerves enterming the hindlimb.
Specimen 5B Pbx1-/-;Pbx2+/-: embryonic day 12.25; \Pbx1tm1Mlc/\Pbx1tm1Mlc, \Pbx2tm1Mlc/\Pbx2+ (more )
Structure Level Pattern Image Note
TS20: peripheral nerve Present Regionally restricted 5B Pbx1-/-;Pbx2+/- Severely compromised neurogenesis more caudally along embryo, specifically in lateral and ventral extent of projecting neural fibers, compared to wild type. No expresssion in peripheral nerves entering the hindlimb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory