Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6391104
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:

anti-Caspase3

Results

S3C E11.5 WT ©

Specimen Caspase3 WT: embryonic day 11.5 (more

)

Structure	Level	Image
TS19: dorsal root ganglion	Present	S3C E11.5 WT , 4A Caspase3 WT
TS19: notochord	Present	S3C E11.5 WT , 4A Caspase3 WT
TS19: vertebral pre-cartilage condensation	Present	S3C E11.5 WT , 4A Caspase3 WT

Specimen Caspase3 Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2⁺ (more

)

Structure	Level	Image	Note
TS19: dorsal root ganglion	Present	4A Caspase3 Pbx1-/-;Pbx2+/- , S3C E11.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.
TS19: notochord	Present	4A Caspase3 Pbx1-/-;Pbx2+/- , S3C E11.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.
TS19: vertebral pre-cartilage condensation	Present	4A Caspase3 Pbx1-/-;Pbx2+/- , S3C E11.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.

S3C E12.5 WT ©

Specimen S3C E12.5 WT: embryonic day 12.5 (more

)

Structure	Level	Image
TS20: dorsal root ganglion	Present	S3C E12.5 WT
TS20: notochord	Present	S3C E12.5 WT
TS20: vertebral pre-cartilage condensation	Present	S3C E12.5 WT

Specimen S3C E12.5 Pbx1-/-;Pbx2+/-: embryonic day 12.5; Pbx1^tm1Mlc/Pbx1^tm1Mlc, Pbx2^tm1Mlc/Pbx2⁺ (more

)

Structure	Level	Image	Note
TS20: dorsal root ganglion	Present	S3C E12.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.
TS20: notochord	Present	S3C E12.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.
TS20: vertebral pre-cartilage condensation	Present	S3C E12.5 Pbx1-/-;Pbx2+/-	No difference in expression between WT and mutant notochord and veretebral anlage. Higher levels of expression equally present in wild type and mutant dorsal root ganglia.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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