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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: RNA in situ
MGI Accession ID: MGI:6391096
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: Col2a probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7D Col2a E12 WT: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present 7D Col2a E12 WT Expression in vertebral bodies.
Specimen 7D Col2a E12 Pbx1-/-;Pbx1-/-: embryonic day 12.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present 7D Col2a E12 Pbx1-/-;Pbx2+/- Expression in vertebral bodies relatively unchanged compared to wild type.
Specimen 7D Col2a Cerv-Thor E12 WT: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present 7D Col2a E12 Cerv-Thor WT Expression in vertebral bodies.
Specimen 7D Col2a Cerv-Thor E12 Pbx1-/-;Pbx2+/-: embryonic day 12.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS20: vertebral cartilage condensation Present 7D Col2a E12 Cerv-Thor Pbx1-/-;Pbx2+/- Expression in vertebral bodies relatively unchanged compared to wild type.
Specimen 7D Col2a Thor E13 WT: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: thoracic vertebral cartilage condensation Present 7D Col2a E13 Thor WT
Specimen 7D Col2a Thor E13 Pbx1-/-;Pbx2+/-: embryonic day 13.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS21: thoracic vertebral cartilage condensation Present 7D Col2a E13 Thor Pbx1-/-;Pbx2+/- Expression undaltered in thoracic vertebral structures compared to wild type.
Specimen 7D Col2a Caud E13 WT: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: tail vertebral cartilage condensation Present 7D Col2a E13 Caud WT
Specimen 7D Col2a Caud E13 Pbx1-/-;Pbx2+/-: embryonic day 13.0; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS21: tail vertebral cartilage condensation Present 7D Col2a E13 Caud Pbx1-/-;Pbx2+/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory