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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: RNA in situ
MGI Accession ID: MGI:6391093
Gene symbol: Pax1
Gene name: paired box 1
Probe: CX10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 7A Pax1 E9 WT: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: somite Present 7A Pax1 E9 WT

Specimen 7A Pax1 E9.5 WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Present 7A Pax1 E9.5 WT

Specimen 7A Pax1 E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present 7A Pax1 E10.5 WT

Specimen 7A Pax1 E10.5 Pbx1-/-;Pbx1-/-: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2tm1Mlc (more )
Structure Level Pattern Image Note
TS17: somite Absent 7A Pax1 E10.5 Pbx1-/-;Pbx2-/-

Specimen 7A Pax1 E10.75 Pbx1-/-;Pbx1-/-: embryonic day 10.75; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2tm1Mlc (more )
Structure Level Pattern Image Note
TS17: somite Absent 7A Pax1 E10.75 Pbx1-/-;Pbx2-/-

Specimen 7B WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present 7B WT
TS19: hindlimb bud Present 7B WT
TS19: somite Present 7B WT

Specimen 7B WT FL: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Present 7B WT FL

Specimen 7B WT HL: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: sclerotome Present 7B WT HL

Specimen 7B Pbx1-/-;Pbx2+/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: forelimb bud Weak 7B Pbx1-/-;Pbx2+/- Expression down-regulated in forelimb;.
TS19: hindlimb bud Absent 7B Pbx1-/-;Pbx2+/- Expression absent from proximal hindlimb.
TS19: somite Present Regionally restricted 7B Pbx1-/-;Pbx2+/- Expression down-regulated in lumbar-sacral domains. Expression spatially restricted to caudal somites.

Specimen 7B Pbx1-/-;Pbx2+/- FL: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: sclerotome Present Diffuse 7B Pbx1-/-;Pbx2+/- FL Expression spatially diffuse in sclerotome.

Specimen 7B Pbx1-/-;Pbx2+/- HL: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: sclerotome Present Diffuse 7B Pbx1-/-;Pbx2+/- HL Expression spatially diffuse in sclerotome.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory