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Gene Expression Data
Assay Details
Assay
Reference: J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
Assay type: RNA in situ
MGI Accession ID: MGI:6391091
Gene symbol: Bmi1
Gene name: Bmi1 polycomb ring finger oncogene
Probe: Bmi probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6B Bmi E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present 6B Bmi E10.5 WT
Specimen 6B Bmi E10.5 Pbx1-/-;Pbx2+/-: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS17: somite Weak Regionally restricted 6B Bmi E10.5 Pbx1-/-;Pbx2+/- Extent of expression severely reduced along entire posterior embryo.
Specimen 6B HL Bmi E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: somite Present 6B Bmi HL E10.5 WT
TS17: nervous system Present 6B Bmi HL E10.5 WT Expression in neurectoderm.
Specimen 6B HL Bmi E10.5 Pbx1-/-;Pbx2+/-: embryonic day 10.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS17: somite Weak Regionally restricted 6B Bmi HL E10.5 Pbx1-/-;Pbx2+/- Expression specifically reduced, if not absent, in somites adjacent to hindlimb buds.
TS17: nervous system Present 6B Bmi HL E10.5 Pbx1-/-;Pbx2+/- Expression in neurectoderm.
Specimen 6B HL Bmi E11.5 WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: somite Present 6B Bmi HL E11.5 WT
Specimen 6B HO Bmi E11.5 Pbx1-/-;Pbx1+/-: embryonic day 11.5; Pbx1tm1Mlc/Pbx1tm1Mlc, Pbx2tm1Mlc/Pbx2+ (more )
Structure Level Pattern Image Note
TS19: somite Weak Regionally restricted 6B Bmi HL E11.5 Pbx1-/-;Pbx2+/- Expression specifically reduced, if not absent, in somites adjacent to hindlimb buds.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory