Gene Expression Data
Assay Details
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Assay
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Reference:
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J:174050
Rakic S, et al., Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Cereb Cortex. 2009 Aug;19(8):1857-69
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6388782
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Gene symbol:
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Lhx6
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Gene name:
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LIM homeobox protein 6
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Antibody:
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Anti-Lhx6
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
6E:
embryonic day 18.5
(more  )
Specimen
6E:
(close  )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex marginal zone |
Present |
Uniform |
6E
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Immunopositive migrating and differentiated cortical interneurons were found evenly distributed in Layer I (marginal zone), cortical plate and subplate.
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| TS26: cortical plate |
Present |
Uniform |
6E
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Immunopositive migrating and differentiated cortical interneurons were found evenly distributed in Layer I (marginal zone), cortical plate and subplate.
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| TS26: cortical subplate |
Present |
Uniform |
6E
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Immunopositive migrating and differentiated cortical interneurons were found evenly distributed in Layer I (marginal zone), cortical plate and subplate.
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Specimen
6H:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Cdk5r1tm1Lht/Cdk5r1tm1Lht
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex |
Present |
Non-Uniform |
6H
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Immunopositive migrating and differentiated cortical interneurons were found in all layers, but were mostly accumulated in the Layer I of the mutant.
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| TS26: cerebral cortex marginal zone |
Present |
Non-Uniform |
6H
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Immunopositive migrating and differentiated cortical interneurons were found in all layers, but were mostly accumulated in the Layer I of the mutant.
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Specimen
7C:
(close )
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Genetic Background:
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involves: 129S4/SvJae * C57BL/6
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Mutant Allele(s):
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Cdk5tm1Kul/Cdk5tm1Kul
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex marginal zone |
Present |
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7C
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In the Cdk5-/- cortex, layer I showed an abnormal accumulation of immunopositive interneurons.
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Specimen
7F:
(close )
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Genetic Background:
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involves: CD-1
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Mutant Allele(s):
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Relnrl/Relnrl
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex |
Present |
Regionally restricted |
7F
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The reeler mutant superplate contained an abundance of immunopositive cells.
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Analysis Tools
