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Gene Expression Data
Assay Details
Assay
Reference: J:135657 Hayashi T, et al., Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99
Assay type: RNA in situ
MGI Accession ID: MGI:6385187
Gene symbol: Hey1
Gene name: hairy/enhancer-of-split related with YRPW motif 1
Probe: Hesr1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlear duct Present Regionally restricted 1A
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cochlear duct Present Regionally restricted 1D
Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 1F In basal region of cochlea, expression divided into a robust band and a region of faint expression in the greater epithelial ridge (GER)
Specimen 1H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cochlear duct Present Regionally restricted 1H Expression in all turns of cochlea.
TS24: greater epithelial ridge Weak 1H
Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear duct Present Regionally restricted Expression in all turns of cochlea.
Specimen 1J inset: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 1J inset Expression in all turns of cochlea.
Specimen 1J: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cochlear duct Present Regionally restricted 1J Expression selectively in Deiters' cells.
Specimen S1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: vestibular component epithelium Present Regionally restricted S1A Expression in epithelium in posterior half of otocyst, which gives rise to vestibular epithelium.
Specimen S1D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: posterior semicircular canal epithelium Present Regionally restricted S1D Expression in all sensory patches in vestibular epithelium.
Specimen S1H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: saccule Present Regionally restricted S1H Expression in all sensory patches in vestibular epithelium.
Specimen 4C: embryonic day 13.5 (more )
Note: Double labeled: purple - Hesr1 (Hey1); red - p27kip1 (Cdkn1b assay MGI:6385184).
Structure Level Pattern Image Note
TS21: cochlear duct Present Regionally restricted 4C Expression in middle part of cochlear duct. Expression domain extends over broader area than that of p27kip1 (Cdkn1b) both medially and laterally.
Specimen 4D: embryonic day 15.5 (more )
Note: Double labeled: purple - Hesr1 (Hey1); red - p27kip1 (Cdkn1b assay MGI:6385184).
Structure Level Pattern Image Note
TS23: cochlear duct Present Regionally restricted 4D Expression in basal turn (turn 1). Expression more restricted, largely overlapping with that of p27kip1 (Cdkn1b) but with some more medial expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory