Sox2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:194917 Juuri E, et al., Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development. 2013 Apr;140(7):1424-32
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6382176
Gene symbol:	Sox2
Gene name:	SRY (sex determining region Y)-box 2

Antibody:	anti-Sox2
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

2F ©

Specimen 2F: embryonic day 12.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: dental placode	Present	Regionally restricted	2F	Expression is in the dental epithelium.
TS20: oral epithelium	Present		2F

2G ©

Specimen 2G: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: lower jaw molar epithelium	Present	Regionally restricted	2G	Expression is in the lingual dental epithelium.
TS22: oral epithelium	Present	Regionally restricted	2G	Expression is at the lingual side of the tooth germ and continued to the lingual cells of the dental cord and enamel organ.
TS22: lower jaw molar enamel organ	Present	Regionally restricted	2G	Expression is in the outer enamel epithelium.
TS22: lower jaw molar dental lamina	Present		2G
TS22: stellate reticulum	Present		2G

2H ©

Specimen 2H: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: lower jaw molar epithelium	Present	Regionally restricted	2H	Expression is in the lingual dental epithelium including in an epithelial protrusion at the junction between the dental cord and outer enamel epithelium at the lingual aspect of the molar.
TS24: oral epithelium	Present	Regionally restricted	2H	Expression is at the lingual side of the tooth germ and continued to the lingual cells of the dental cord and enamel organ.
TS24: lower jaw molar enamel organ	Present	Regionally restricted	2H	Expression is in the outer enamel epithelium.
TS24: lower jaw molar dental lamina	Present		2H
TS24: stellate reticulum	Present		2H

5B ©

Specimen 5B: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present	Regionally restricted	5B	Expression is in the lingual dental epithelium including in an epithelial protrusion at the junction between the dental cord and outer enamel epithelium at the lingual aspect of the molar.
TS26: lower jaw molar dental lamina	Present	Regionally restricted	5B	Expression extends from the dental cord to the dental lamina connecting molar 1 and molar 2.
TS26: oral epithelium	Present	Regionally restricted	5B	Expression extends from the dental cord to the dental lamina connecting molar 1 and molar 2.

Specimen not shown: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present	Regionally restricted		Expression is in the lingual dental epithelium including in an epithelial protrusion at the junction between the dental cord and outer enamel epithelium at the lingual aspect of the molar.
TS25: lower jaw molar dental lamina	Present

S4_E17 Control M1 ©

Specimen S4 E17 M1: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Control M1

S4_E17 Control M2 ©

Specimen S4 E17 M2: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Control M2

S4_E17 Control M3 ©

Specimen S4 E17 M3: embryonic day 17.5 (more

)

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Control M3

S4_E17 Sox2cKO 1 M1 ©

Specimen E17 Sox2cKO 1 M1: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 1 M1

S4_E17 Sox2cKO 1 M2 ©

Specimen E17 Sox2cKO 1 M2: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 1 M2

S4_E17 Sox2cKO 1 M3 ©

Specimen E17 Sox2cKO 1 M3: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 1 M3

S4_E17 Sox2cKO 2 M1 ©

Specimen E17 Sox2cKO 2 M1: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 2 M1

S4_E17 Sox2cKO 2 M2 ©

Specimen E17 Sox2cKO 2 M2: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 2 M2

S4_E17 Sox2cKO 2 M3 ©

Specimen E17 Sox2cKO 2 M3: embryonic day 17.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS25: lower jaw molar epithelium	Present		S4_E17 Sox2cKO 2 M3

S4_E18 Control M1 ©

Specimen E18 Control M1: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Control M1

S4_E18 Control M2 ©

Specimen E18 Control M2: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Control M2

Specimen E18 Control M3: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Control M3

Specimen E18 Sox2cKO 1 M1: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 1 M1

Specimen E18 Sox2cKO 1 M2: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 1 M2

Specimen E18 Sox2cKO 1 M3: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 1 M3

Specimen E18 Sox2cKO 2 M1: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 2 M1

Specimen E18 Sox2cKO 2 M2: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 2 M2

Specimen E18 Sox2cKO 2 M3: embryonic day 18.5; Shh^{tm1(EGFP/cre)Cjt}/Shh⁺, Sox2^tm1.1Lan/Sox2^tm1.1Lan (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS26: lower jaw molar epithelium	Present		S4_E18 Sox2cKO 2 M3

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