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Gene Expression Data
Assay Details
Assay
Reference: J:130185 Ellsworth BS, et al., Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6380644
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-ISL1
Detection system: fluorescein
Results
Specimen 4G: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future adenohypophysis Present 4G Expression in invaginating oral ectoderm.

Specimen 4H: embryonic day 9.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS15: future adenohypophysis Present 4H Expression in invaginating oral ectoderm.

Specimen E10.5 Wild type not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future adenohypophysis Present

Specimen E10.5 Mutant not shown: embryonic day 10.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS17: future adenohypophysis Present

Specimen 4I: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: adenohypophysis pars anterior Present 4I

Specimen 4J: embryonic day 12.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS20: pituitary gland Absent 4J Expression transiently lost at E12.5

Specimen E14.5 Wild type not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: adenohypophysis pars anterior Present

Specimen E14.5 Mutant not shown: embryonic day 14.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS22: pituitary gland Present

Specimen E16.5 Wild type not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: adenohypophysis pars anterior Present

Specimen E16.5 Mutant not shown: embryonic day 16.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS24: pituitary gland Present Regionally restricted Authors report ectopic expression in dorsal aspect of mutant pituitary.

Specimen 4K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: adenohypophysis pars anterior Present 4K

Specimen 4L: embryonic day 18.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd (more )
Structure Level Pattern Image Note
TS26: pituitary gland Present Regionally restricted 4L Authors report ectopic expression in dorsal aspect of mutant pituitary.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory