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Gene Expression Data
Assay Details
Assay
Reference: J:276389 Li M, et al., Ythdf2-mediated m(6)A mRNA clearance modulates neural development in mice. Genome Biol. 2018 May 31;19(1):69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379682
Gene symbol: Dcx
Gene name: doublecortin
Antibody: anti-Dcx (ab18723)
Detection system: Secondary antibody
Results
Specimen 2c WT E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 2c E12.5 WT left , 2c E12.5 WT right Expression is in a layer of immature neurons.
Specimen 2c Ythdf2+/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 2c E12.5 +/- left , 2c E12.5 +/- right The thickness of the cortex and the layer of expression is reduced in this mutant.
Specimen 2c Ythdf2-/- E12.5: embryonic day 12.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 2c E12.5 -/- right , 2c E12.5 -/- left The thickness of the cortex and the layer of expression is reduced in this mutant.
Specimen 2c WT E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 2c E14.5 WT left , 2c E14.5 WT right Expression is in a layer of immature neurons.
Specimen 2c Ythdf2+/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2+ (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 2c E14.5 +/- left , 2c E14.5 +/- right The thickness of the cortex and the layer of expression is reduced in this mutant.
Specimen 2c Ythdf2-/- E14.5: embryonic day 14.5; Ythdf2em1.1Klng/Ythdf2em1.1Klng (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 2c E14.5 -/- right , 2c E14.5 -/- left The thickness of the cortex and the layer of expression is reduced in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory