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Gene Expression Data
Assay Details
Assay
Reference: J:108519 Waters ST, et al., A threshold requirement for Gbx2 levels in hindbrain development. Development. 2006 May;133(10):1991-2000
Assay type: RNA in situ
MGI Accession ID: MGI:6378596
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe89
Probe preparation: Antisense RNA
Results
Specimen 2A: embryonic day 9.0 (more )
Note: 14 somite stage embryo. Also stained for Egr2 (assay MGI:6378597).
Structure Level Pattern Image Note
TS14: rhombomere 1 Present 2A

Specimen 2B: embryonic day 9.0; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: 14 somite stage embryo. Also stained for Egr2 (assay MGI:6378597).
Structure Level Pattern Image Note
TS14: rhombomere 1 Present 2B Expression in this mutant is the same as in wild-type embryos.

Specimen 5C: embryonic day 8.5 (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 5C Expression is in the rostral end of the prospective hindbrain.

Specimen 5D: embryonic day 8.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Note: 10 somite stage embryo.
Structure Level Pattern Image Note
TS13: future hindbrain Present 5D There is a broad caudal expansion of expression in this mutant.

Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 6A Expression is in adjacent narrow transverse rings at the mid/hindbrain boundary.
TS17: midbrain Present Regionally restricted 6A Expression is in adjacent narrow transverse rings at the mid/hindbrain boundary.
TS17: midbrain-hindbrain junction Present 6A

Specimen 6A inset: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 6A inset Expression is in adjacent narrow transverse rings at the mid/hindbrain boundary.
TS17: midbrain Present Regionally restricted 6A inset Expression is in adjacent narrow transverse rings at the mid/hindbrain boundary.
TS17: midbrain-hindbrain junction Present 6A inset

Specimen 6B: embryonic day 10.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 6B In this mutant expression extends caudally through the dorsal midline of the isthmus and alar plate of rhombomere 1, and mediolaterally into the anterior rhombic lip.
TS17: rhombomere 1 Present Regionally restricted 6B In this mutant expression extends caudally through the dorsal midline of the isthmus and alar plate of rhombomere 1, and mediolaterally into the anterior rhombic lip.
TS17: midbrain-hindbrain junction Present 6B

Specimen 6B inset: embryonic day 10.5; Gbx2tm1Mrt/Gbx2tm1Mrt (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 6B inset In this mutant expression extends caudally through the dorsal midline of the isthmus and alar plate of rhombomere 1, and mediolaterally into the anterior rhombic lip.
TS17: rhombomere 1 Present Regionally restricted 6B inset In this mutant expression extends caudally through the dorsal midline of the isthmus and alar plate of rhombomere 1, and mediolaterally into the anterior rhombic lip.
TS17: midbrain-hindbrain junction Present 6B inset

Specimen 7A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain-hindbrain junction Present 7A

Specimen 7B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 7B There is ectopic expression in the anterior rhombic lip.
TS17: rhombomere 1 Present Regionally restricted 7B There is ectopic expression in the anterior rhombic lip.
TS17: midbrain-hindbrain junction Present 7B


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory