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Gene Expression Data
Assay Details
Assay
Reference: J:126341 Nam JS, et al., Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Dev Biol. 2007 Nov 1;311(1):124-35
Assay type: RNA in situ
MGI Accession ID: MGI:6377620
Gene symbol: Axin2
Gene name: axin 2
Probe: Axin2 probe13
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6D
Specimen 6E: embryonic day 11.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6E
Specimen 6F: embryonic day 11.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Trace 6F Expression significantly reduced or eliminated in apical ectodermal ridge of -/- embryos.
Specimen 6G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6G
TS19: hindlimb bud mesenchyme Present Regionally restricted 6G Expression in limb mesenchymal cells underneath surface ectoderm outside the apical ectodermal ridge.
Specimen 6H: embryonic day 11.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6H
TS19: hindlimb bud mesenchyme Present Regionally restricted 6H Expression in limb mesenchymal cells underneath surface ectoderm outside the apical ectodermal ridge.
Specimen 6I: embryonic day 11.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Trace 6I Expression significantly reduced or eliminated in apical ectodermal ridge of -/- embryos.
TS19: hindlimb bud mesenchyme Present Regionally restricted 6I Mesenchymal expression relatively unchanged in all embryos examined.
Specimen 6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6J
TS19: hindlimb bud mesenchyme Present Regionally restricted 6J Expression in limb mesenchymal cells underneath surface ectoderm outside the apical ectodermal ridge.
Specimen 6K: embryonic day 11.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 6K
TS19: hindlimb bud mesenchyme Present Regionally restricted 6K Expression in limb mesenchymal cells underneath surface ectoderm outside the apical ectodermal ridge.
Specimen 6L: embryonic day 11.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Trace 6L Expression significantly reduced or eliminated in apical ectodermal ridge of -/- embryos.
TS19: hindlimb bud mesenchyme Present Regionally restricted 6L Mesenchymal expression relatively unchanged in all embryos examined.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory