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Gene Expression Data
Assay Details
Assay
Reference: J:126341 Nam JS, et al., Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Dev Biol. 2007 Nov 1;311(1):124-35
Assay type: RNA in situ
MGI Accession ID: MGI:6377619
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 probe37
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen +/+ forelimb not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present
Specimen +/- forelimb not shown: embryonic day 10.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present
Specimen -/- forelimb not shown: embryonic day 10.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS17: forelimb bud apical ectodermal ridge Present Normal expression in forelimb.
Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 4A
Specimen 4B: embryonic day 10.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 4B
Specimen 4C: embryonic day 10.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Trace 4C Reduced and disrupted expression in hindlimb.
Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 4D
Specimen 4E: embryonic day 10.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present 4E
Specimen 4F: embryonic day 10.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Trace Regionally restricted 4F Reduced and disrupted expression in hindlimb.
Specimen 4G: embryonic day 11.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 4G
Specimen 4H: embryonic day 11.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Trace Regionally restricted 4H Reduced and disrupted expression in hindlimb.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory