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Gene Expression Data
Assay Details
Assay
Reference: J:126341 Nam JS, et al., Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Dev Biol. 2007 Nov 1;311(1):124-35
Assay type: RNA in situ
MGI Accession ID: MGI:6377610
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 probe47
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4I: embryonic day 10.25; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS16: hindlimb bud mesenchyme Present Regionally restricted 4I Expression in mesenchymal cells underlying the apical ectodermal ridge.
Specimen 4J: embryonic day 10.25; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS16: hindlimb bud mesenchyme Present Regionally restricted 4J Expression appears unchanged compared to wild type embryos.
Specimen 4K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS16: hindlimb bud mesenchyme Present Regionally restricted 4K Expression in mesenchymal cells underlying the apical ectodermal ridge.
Specimen 4L: embryonic day 10.5; Rspo2tm1Nuv/Rspo2+ (more )
Structure Level Pattern Image Note
TS16: hindlimb bud mesenchyme Present Regionally restricted 4L Expression in mesenchymal cells underlying the apical ectodermal ridge.
Specimen 4M: embryonic day 10.5; Rspo2tm1Nuv/Rspo2tm1Nuv (more )
Structure Level Pattern Image Note
TS16: hindlimb bud mesenchyme Weak Regionally restricted 4M Clearly reduced expression, especially in left hindlimbs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory