Gene Expression Data
Assay Details
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Assay
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Reference:
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J:124124
Core N, et al., Tshz1 is required for axial skeleton, soft palate and middle ear development in mice. Dev Biol. 2007 Aug 15;308(2):407-20
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6377489
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Gene symbol:
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Runx2
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Gene name:
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runt related transcription factor 2
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Probe:
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Cbfa1 cDNA7
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
9I:
embryonic day 12.5
(more  )
Specimen
9I:
(close  )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: middle ear mesenchyme |
Present |
Regionally restricted |
9I
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Expression around Meckel's cartilage. Expression in mesenchymal cells caudal to tubo-tympanic recess.
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Specimen
9J:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * CD-1
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Mutant Allele(s):
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Tshz1tm1Core/Tshz1tm1Core
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: middle ear mesenchyme |
Present |
Regionally restricted |
9J
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Expression around Meckel's cartilage. No expression in mesenchymal cells caudal to tubo-tympanic recess.
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Specimen
9K:
embryonic day 13.5
(more )
Specimen
9K:
(close )
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Genetic Background:
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involves: C57BL/6J * CD-1
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: middle ear mesenchyme |
Present |
Regionally restricted |
9K
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Expression around Meckel's cartilage. Expression in mesenchymal cells caudal to tubo-tympanic recess.
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Specimen
9L:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * CD-1
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Mutant Allele(s):
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Tshz1tm1Core/Tshz1tm1Core
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: middle ear mesenchyme |
Present |
Regionally restricted |
9L
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Expression around Meckel's cartilage. Strongly reduced expression in mesenchymal cells caudal to tubo-tympanic recess.
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Analysis Tools
