Gene Expression Data
Assay Details
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Assay
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Reference:
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J:122558
Yu L, et al., Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. Dev Biol. 2007 Jun 15;306(2):549-59
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6377423
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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Bmp4 cDNA35
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6A:
embryonic day 11.5
(more  )
Specimen
6A:
(close  )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: future arm mesenchyme |
Present |
Regionally restricted |
6A
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Expression in mesenchymal condensations of stulopod and zeugopod.
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Specimen
6B:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Shox2tm1Ypc/Shox2tm1Ypc
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: upper arm mesenchyme |
Present |
Regionally restricted |
6B
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Ectopic expression in mesenchymal tissues surrounding humerus condensation.
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Specimen
6C:
embryonic day 12.5
(more )
Specimen
6C:
(close )
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Genetic Background:
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involves: C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: upper arm rest of mesenchyme |
Present |
Regionally restricted |
6C
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Expression restricted to perichondrium and surrounding mesenchyme, with higher levels at both ends of humerus.
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Specimen
6D:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Shox2tm1Ypc/Shox2tm1Ypc
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: upper arm rest of mesenchyme |
Strong |
Regionally restricted |
6D
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Expression markedly upregulated in mesenchymal tissues surrounding humerus. Strong expression in perichondrial region.
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Analysis Tools
