Sox9 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178421 Dowdle WE, et al., Disruption of a ciliary B9 protein complex causes Meckel syndrome. Am J Hum Genet. 2011 Jul 15;89(1):94-110
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6370132
Gene symbol:	Sox9
Gene name:	SRY (sex determining region Y)-box 9

Antibody:

anti-Sox9

Results

Specimen 1D +/+: postnatal day 1 (more

)
Note: Triple labeled: red - Sox9; green - Cdh1 (assay MGI:6370133); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS27: bile duct	Present		1D +/+

Specimen 1D -/-: postnatal day 1; B9d1^{tm1d(EUCOMM)Wtsi}/B9d1^{tm1d(EUCOMM)Wtsi} (more

)
Note: Triple labeled: red - Sox9; green - Cdh1 (assay MGI:6370133); blue - DAPI.

Structure	Level	Pattern	Image	Note
TS27: bile duct	Present	Regionally restricted	1D -/-	Authors report ductal plate fails to remodel, resulting in hyperplastic portal mesenchyme and separation of enlarged bile ducts from central portal vein.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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