Gene Expression Data
Assay Details
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Assay
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Reference:
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J:228706
Chandramouli A, et al., Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution. Breast Cancer Res. 2013;15(6):R111
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6369618
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Gene symbol:
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Ltbp1
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Gene name:
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latent transforming growth factor beta binding protein 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A:
embryonic day 10.5; Ltbp1tm1Vlcg/Ltbp1 +
(more  )
Specimen
2A:
(close  )
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Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
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Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
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|
Age:
|
embryonic day 10.5
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|
Sex:
|
Not Specified
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|
Type:
|
whole mount
|
|
Fixation:
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4% Paraformaldehyde
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Specimen
2B:
embryonic day 10.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Vibratome section.
Specimen
2B:
(close )
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Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
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Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 10.5
|
|
Sex:
|
Not Specified
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|
Type:
|
section
|
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Gelatin
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Note:
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Vibratome section.
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Specimen
2C:
embryonic day 12.0-12.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
2C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
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|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 12.0-12.5
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|
Sex:
|
Not Specified
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|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
2C
|
Expression is in a streak along the forelimb axilla and surrounding placodes 1 to 3.
|
Specimen
2D:
embryonic day 12.0-12.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
2D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 12.0-12.5
|
|
Sex:
|
Not Specified
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|
Type:
|
section
|
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Fixation:
|
4% Paraformaldehyde
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|
Embedding:
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Gelatin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: trunk mesenchyme |
Present |
Regionally restricted |
2D
|
Expression is in a gradient in the mesenchyme oriented towards mammary gland 1.
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Specimen
3A:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
3A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
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Sex:
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Female
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Type:
|
whole mount
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|
Fixation:
|
4% Paraformaldehyde
|
Specimen
3B:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
3B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
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Sex:
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Male
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Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
3C:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Trp63 (assay MGI:6369720).
Specimen
3C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
|
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Sex:
|
Not Specified
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Type:
|
section
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Fixation:
|
4% Paraformaldehyde
|
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Embedding:
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Paraffin
|
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Note:
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Double labeled: blue - Ltbp1 reporter; brown - Trp63 (assay MGI:6369720).
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Specimen
3D:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Krt14 (assay MGI:6369721).
Specimen
3D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
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|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
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Paraffin
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Note:
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Double labeled: blue - Ltbp1 reporter; brown - Krt14 (assay MGI:6369721).
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Specimen
3E:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Esr1 (assay MGI:6369722).
Specimen
3E:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
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Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
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Double labeled: blue - Ltbp1 reporter; brown - Esr1 (assay MGI:6369722).
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Specimen
3F:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Ar (assay MGI:6369723).
Specimen
3F:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
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Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
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Note:
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Double labeled: blue - Ltbp1 reporter; brown - Ar (assay MGI:6369723).
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Specimen
3G:
embryonic day 14.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Lef1 (assay MGI:6369724).
Specimen
3G:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 14.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
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Double labeled: blue - Ltbp1 reporter; brown - Lef1 (assay MGI:6369724).
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Specimen
4A:
embryonic day 16.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
4A:
(close )
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Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
4B:
embryonic day 16.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
4B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
4C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal day 1
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Sex:
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Female
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Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: mammary gland smooth muscle |
Present |
Regionally restricted |
4C
|
Expression is in smooth muscle cells at the base of the nipple shield extending radially into the developing areola.
|
Specimen
4D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
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Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal day 1
|
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Sex:
|
Female
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|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: mammary gland smooth muscle |
Present |
Regionally restricted |
4D
|
Expression is in smooth-muscle cells at the base of the nipple shield extending radially into the developing areola.
|
Specimen
5A:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Virgin mouse.
Specimen
5A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Virgin mouse.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Strong |
Regionally restricted |
5A
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
| TS28: nipple |
Present |
Regionally restricted |
5A
|
Absent in nipple stromal cells at most developmental ages (shown) and is present during mid-pregnancy.
|
Specimen
5B:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 14.5.
Specimen
5B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 14.5.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Strong |
Regionally restricted |
5B
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
Specimen
5B':
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 14.5.
Specimen
5B':
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 14.5.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Present |
Regionally restricted |
5B'
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
Specimen
5C:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 13.5. Double labeled: blue - Ltbp1 reporter; brown - Acta2 (assay MGI:6369727).
Specimen
5C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 13.5. Double labeled: blue - Ltbp1 reporter; brown - Acta2 (assay MGI:6369727).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Strong |
Regionally restricted |
5C
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
Specimen
5C':
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 13.5.
Specimen
5C':
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 13.5.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Strong |
Regionally restricted |
5C'
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
Specimen
5D:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1; purple - elastin fibers.
Specimen
5D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Double labeled: blue - Ltbp1; purple - elastin fibers.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Present |
Regionally restricted |
5D
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
Specimen
5E:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 13.5.
Specimen
5E:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 13.5.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland smooth muscle |
Present |
Regionally restricted |
5E
|
Expression is in bands of smooth-muscle cells at the base of the nipple underlying the areola in the region of the nipple sphincter.
|
| TS28: nipple |
Present |
Regionally restricted |
5E
|
Absent in nipple stromal cells at most developmental ages and is present during mid-pregnancy (shown).
|
Specimen
5F:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 15.5. Double labeled: blue - Ltbp1 reporter; brown - Vim (assay MGI:6369731).
Specimen
5F:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 15.5. Double labeled: blue - Ltbp1 reporter; brown - Vim (assay MGI:6369731).
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: nipple |
Present |
Regionally restricted |
5F
,
5F'
|
Expression is in stromal cells underlying the nipple germinative epithelium just prior to clefting.
|
Specimen
5G:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 16.5.
Specimen
5G:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 16.5.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland duct |
Present |
Regionally restricted |
5G
|
Expression is absent in the region of the lactiferous duct within the nipple and is present as the duct enters the fat pad at the base of the nipple.
|
| TS28: nipple |
Present |
Regionally restricted |
5G
|
Absent in nipple stromal cells at most developmental ages (shown) and is present during mid-pregnancy.
|
Specimen
5H:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involution stage.
Specimen
5H:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Involution stage.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland duct |
Present |
Regionally restricted |
5H
|
Expression is absent in the region of the lactiferous duct within the nipple and is present as the duct enters the fat pad at the base of the nipple.
|
| TS28: nipple |
Present |
Regionally restricted |
5H
|
Absent in nipple stromal cells at most developmental ages (shown) and is present during mid-pregnancy.
|
Specimen
6A:
embryonic day 17.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
6A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 17.5
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6B:
embryonic day 17.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
6B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 17.5
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
6C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
Specimen
6D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal day 1
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS27: mammary gland duct |
Present |
Regionally restricted |
6D
|
Expression is in luminal cells in the microlumen and is absent in the stratified epithelium of the lactiferous duct within the nipple.
|
| TS27: mammary gland smooth muscle |
Present |
Regionally restricted |
6D
|
Expression is in the developing smooth muscle cells of the nipple areola.
|
Specimen
6E:
embryonic day 18.5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Specimen
6E:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
embryonic day 18.5
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: mammary sprout |
Present |
Regionally restricted |
6E
|
Expression is absent from the bulbous multilayered tips.
|
Specimen
7C:
postnatal week 5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Virgin mouse.
Specimen
7C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal week 5
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Virgin mouse.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary duct terminal end bud |
Present |
|
7C
|
Expression is punctate in a subset of luminal cells in the internal portion of the terminal end bud and is surrounded by non-expressing cap and body cell layers.
|
Specimen
7D:
postnatal week 5; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Virgin mouse.
Specimen
7D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal week 5
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Virgin mouse.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary duct terminal end bud |
Present |
|
7D
|
Expression is in a subset of luminal cells in the internal portion of the terminal end bud and is surrounded by non-expressing cap and body cell layers.
|
Specimen
8A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
8B inset:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Double labeled: blue - Ltbp1 reporter; brown - Trp63 (assay MGI:6369720).
Specimen
8B inset:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Double labeled: blue - Ltbp1 reporter; brown - Trp63 (assay MGI:6369720).
|
Specimen
9A:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 13.5.
Specimen
9A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Pregnancy day 13.5.
|
Specimen
9B:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 13.5.
Specimen
9B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Pregnancy day 13.5.
|
Specimen
9C:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 14.5.
Specimen
9C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Pregnancy day 14.5.
|
Specimen
9D:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 14.5.
Specimen
9D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Pregnancy day 14.5.
|
Specimen
9E:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 16.5.
Specimen
9E:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 16.5.
|
Specimen
9F:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Pregnancy day 16.5.
Specimen
9F:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Pregnancy day 16.5.
|
Specimen
10A:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Lactating mouse.
Specimen
10A:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Lactating mouse.
|
Specimen
10B:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Lactating mouse.
Specimen
10B:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Lactating mouse.
|
Specimen
10C:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involuting glands removed 24 hours after pup weaning.
Specimen
10C:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Involuting glands removed 24 hours after pup weaning.
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS28: mammary gland duct |
Present |
Regionally restricted |
10C
|
Expression is along the main ducts and distended primary side branches.
|
Specimen
10D:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involuting glands removed 24 hours after pup weaning.
Specimen
10D:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Involuting glands removed 24 hours after pup weaning.
|
Specimen
10E:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involuting glands removed 72 hours after pup weaning.
Specimen
10E:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
whole mount
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Note:
|
Involuting glands removed 72 hours after pup weaning.
|
Specimen
10F:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involuting glands removed 72 hours after pup weaning.
Specimen
10F:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Involuting glands removed 72 hours after pup weaning.
|
Specimen
10H:
postnatal adult; Ltbp1tm1Vlcg/Ltbp1 +
(more )
Note: Involution day 21.
Specimen
10H:
(close )
|
Genetic Background:
|
involves: 129S/SvEv * C57BL/6 * FVB/N
|
|
Mutant Allele(s):
|
Ltbp1tm1Vlcg/Ltbp1+
|
|
Age:
|
postnatal adult
|
|
Sex:
|
Female
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
|
Note:
|
Involution day 21.
|
|
Analysis Tools