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Gene Expression Data
Assay Details
Assay
Reference: J:121318 Davis SW, et al., Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6369080
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Isl1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present 3C
Specimen 3D: embryonic day 12.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present Regionally restricted 3D Rathke's pouch lacks proper morphology, and domain of expression is displaced rostrally.
Specimen 5D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 5D
Specimen 5E: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 5E
TS17: oral region epithelium Present Regionally restricted 5E Expression throughout multiple invaginations in oral ectoderm.
Specimen 5F: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Tg(Cga-cre)3Sac/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Absent 5F
Specimen 5J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: remnant of Rathke's pouch Present 5J
Specimen 5K: embryonic day 16.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS24: remnant of Rathke's pouch Present 5K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory