About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:121318 Davis SW, et al., Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6369079
Gene symbol: Pitx1
Gene name: paired-like homeodomain transcription factor 1
Antibody: Pitx1 antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present 3A
Specimen 3B: embryonic day 12.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS20: remnant of Rathke's pouch Present Regionally restricted 3B Rathke's pouch lacks proper morphology, and domain of expression is displaced rostrally.
Specimen 4A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pituitary gland Present Regionally restricted 4A Expression in secondary pituitary tissue.
Specimen 4G: embryonic day 17.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS25: pituitary gland Present Regionally restricted 4G Expression in secondary pituitary tissue.
Specimen 4M: embryonic day 18.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS26: pituitary gland Present Regionally restricted 4M Expression in secondary pituitary tissue.
Specimen 4S: embryonic day 18.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS26: pituitary gland Present Regionally restricted 4S Expression in secondary pituitary tissue.
Specimen 5A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 5A
Specimen 5B: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 5B
TS17: oral region epithelium Present Regionally restricted 5B Expression throughout multiple invaginations in oral ectoderm.
Specimen 5C: embryonic day 10.5; Bmpr1atm1Bhr/Bmpr1atm2.1Bhr, Tg(Cga-cre)3Sac/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: Rathke's pouch Present 5C Rathke's pouch is thin and underdeveloped compared to wild type littermates.
Specimen 6J: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 6J
Specimen 6K: embryonic day 11.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Weak Regionally restricted 6K Lower levels of expression in secondary invagination.
Specimen 6L: embryonic day 11.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Weak Regionally restricted 6L Lower levels of expression in secondary invagination.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory