About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
Assay type: RNA in situ
MGI Accession ID: MGI:6368125
Gene symbol: Dbx1
Gene name: developing brain homeobox 1
Probe: c164
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 3U: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3U Authors report expression repressed in the ventral neural tube.
Specimen 3V: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3V Expression shifted ventrally. Expression absent in anterior spinal cord.
Specimen 3W: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3W Authors report expression was normal.
Specimen 3X: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3X
Specimen 3Y: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3Y Authors report expression was normal.
Specimen 3Z: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 3Z Authors report expression repressed in the ventral neural tube.
Specimen 3AA: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent 3AA Expression absent in hindbrain and anterior spinal cord.
Specimen 3BB: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present 3BB
Specimen 3CC: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Weak Regionally restricted 3CC Expression domain slightly reduced and shifted ventrally.
Specimen 3DD: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present 3DD
Specimen S1A: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted S1A Authors state expression was slightly more ventral and disorganized in some mutants.
Specimen S1C: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted S1C Authors state expression was slightly more ventral and disorganized in some mutants.
Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 4C
Specimen 4F: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4F Expression in posterior spinal cord.
TS17: gut Present 4F
Specimen 4O: embryonic day 10.5 (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: hindbrain Present 4O
Specimen 4P: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: hindbrain Present 4P
Specimen 4Q: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 4Q Expression spans midline at rhombomeres 1 and 2.
TS17: rhombomere 2 Present Regionally restricted 4Q Expression spans midline at rhombomeres 1 and 2.
Specimen 4R: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: rhombomere Present Uniform 4R No difference in expression between rhombomeres.
Specimen S3T r2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3T r2
Specimen S3T r4: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3T r4
Specimen S3T r5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3T r5
Specimen S3T r7: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3T r7
Specimen S3U r2: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Absent S3U r2
Specimen S3U r4: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Absent S3U r4
Specimen S3U r5: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent S3U r5
Specimen S3U r7: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Absent S3U r7
Specimen S3V r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present Regionally restricted S3V r2 Expression spans midline at rhombomeres 1 and 2.
Specimen S3V r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3V r4
Specimen S3V r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3V r5
Specimen S3V r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3V r7
Specimen S3W r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3W r2 No difference in expression between rhombomeres.
Specimen S3W r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3W r4 No difference in expression between rhombomeres.
Specimen S3W r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3W r5 No difference in expression between rhombomeres.
Specimen S3W r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3W r7
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory