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Gene Expression Data
Assay Details
Assay
Reference: J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
Assay type: RNA in situ
MGI Accession ID: MGI:6368125
Gene symbol: Dbx1
Gene name: developing brain homeobox 1
Probe: c164
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 3U: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3U Authors report expression repressed in the ventral neural tube.

Specimen 3V: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3V Expression shifted ventrally. Expression absent in anterior spinal cord.

Specimen 3W: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3W Authors report expression was normal.

Specimen 3X: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3X

Specimen 3Y: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 3Y Authors report expression was normal.

Specimen 3Z: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 3Z Authors report expression repressed in the ventral neural tube.

Specimen 3AA: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent 3AA Expression absent in hindbrain and anterior spinal cord.

Specimen 3BB: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present 3BB

Specimen 3CC: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Weak Regionally restricted 3CC Expression domain slightly reduced and shifted ventrally.

Specimen 3DD: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present 3DD

Specimen S1A: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted S1A Authors state expression was slightly more ventral and disorganized in some mutants.

Specimen S1C: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted S1C Authors state expression was slightly more ventral and disorganized in some mutants.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Present 4C

Specimen 4F: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4F Expression in posterior spinal cord.
TS17: gut Present 4F

Specimen 4O: embryonic day 10.5 (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: hindbrain Present 4O

Specimen 4P: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: hindbrain Present 4P

Specimen 4Q: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 4Q Expression spans midline at rhombomeres 1 and 2.
TS17: rhombomere 2 Present Regionally restricted 4Q Expression spans midline at rhombomeres 1 and 2.

Specimen 4R: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Note: After hybridization as whole mounts, hindbrains were dissected out and flattened opened under a coverslip.
Structure Level Pattern Image Note
TS17: rhombomere Present Uniform 4R No difference in expression between rhombomeres.

Specimen S3T r2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3T r2

Specimen S3T r4: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3T r4

Specimen S3T r5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3T r5

Specimen S3T r7: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3T r7

Specimen S3U r2: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Absent S3U r2

Specimen S3U r4: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Absent S3U r4

Specimen S3U r5: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent S3U r5

Specimen S3U r7: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Absent S3U r7

Specimen S3V r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present Regionally restricted S3V r2 Expression spans midline at rhombomeres 1 and 2.

Specimen S3V r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3V r4

Specimen S3V r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3V r5

Specimen S3V r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3V r7

Specimen S3W r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3W r2 No difference in expression between rhombomeres.

Specimen S3W r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3W r4 No difference in expression between rhombomeres.

Specimen S3W r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3W r5 No difference in expression between rhombomeres.

Specimen S3W r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3W r7


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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory