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Gene Expression Data
Assay Details
Assay
Reference: J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6368120
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-Isl1/2
Detection system: horseradish peroxidase
Results
Specimen 2U: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2U Expression in motoneurons in ventral spinal cord.

Specimen 2V: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent 2V Authors state montoneurons are absent.

Specimen 2W: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Weak Regionally restricted 2W Expression in motoneurons in ventral spinal cord shifted ventrally and reduced in number.

Specimen 2X: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Absent 2X Authors state montoneurons are absent.

Specimen 2Y: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Weak Regionally restricted 2Y Expression in motoneurons in ventral spinal cord shifted ventrally and reduced in number.

Specimen 2Z: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2Z Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2AA: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent 2AA Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2BB: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Ambiguous 2BB No or very few expressing cells detected.

Specimen 2CC: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent 2CC Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2DD: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Ambiguous 2DD No or very few expressing cells detected.

Specimen S3F r2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3F r2 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3F r4: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3F r4 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3F r5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3F r5 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3F r7: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3F r7 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3G r2: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Absent S3G r2 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3G r4: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Absent S3G r4 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3G r5: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Absent S3G r5 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3G r7: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Absent S3G r7 Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen S3H r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Ambiguous S3H r2 No or very few expressing cells detected.

Specimen S3H r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Ambiguous S3H r4 No or very few expressing cells detected.

Specimen S3H r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Ambiguous S3H r5 No or very few expressing cells detected.

Specimen S3H r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Ambiguous S3H r7

Specimen S3I r2: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Present S3I r2

Specimen S3I r4: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Present S3I r4

Specimen S3I r5: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present S3I r5

Specimen S3I r7: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Present S3I r7

Specimen S3J r2: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 2 Ambiguous S3J r2 No or very few expressing cells detected.

Specimen S3J r4: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 4 Ambiguous S3J r4 No or very few expressing cells detected.

Specimen S3J r5: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Ambiguous S3J r5 No or very few expressing cells detected.

Specimen S3J r7: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 7 Ambiguous S3J r7 No or very few expressing cells detected.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory