About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:119875 Lebel M, et al., Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain. Dev Biol. 2007 Feb 1;302(1):345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6368119
Gene symbol: Irx3
Gene name: Iroquois related homeobox 3
Antibody: Irx3 antibody
Detection system: alkaline phosphatase
Results
Specimen 2K: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2K Expression domain located immediately to the Olig2 domain, expanded well into the dorsal neural tube.

Specimen 2L: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2L Expression expanded ventrally compared to wildtype, spanning the midline.

Specimen 2M: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2M Authors report normal expression in ventral neural tube.

Specimen 2N: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2N Expression expanded ventrally compared to wildtype. and spanned the midline.

Specimen 2O: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2O Authors report normal expression in ventral neural tube.

Specimen 2P: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2P Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2Q: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2Q Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2R: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2R Expression ventrally expanded and spanned midline.

Specimen 2S: embryonic day 10.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2S Authors state hindbrain expression was similar to that observed in the spinal cord.

Specimen 2T: embryonic day 10.5; Gli3Xt-J/Gli3Xt-J, Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: rhombomere 5 Present Regionally restricted 2T Expression ventrally expanded and spanned midline.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory