Spry1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type:	RNA in situ
MGI Accession ID:	MGI:6363705
Gene symbol:	Spry1
Gene name:	sprouty RTK signaling antagonist 1

Results

5a ©

Specimen 5a: embryonic day 12.5; Fgfr2^tm1Wrst/Fgfr2^tm1Wrst (more

)

Structure	Level	Pattern	Image	Note
TS20: midbrain	Present	Regionally restricted	5a	Ventral expression along entire midbrain-hindbrain region. Dorsal expression in inferior colliculus
TS20: midbrain-hindbrain junction	Present		5a
TS20: hindbrain	Present	Regionally restricted	5a	Ventral expression along entire midbrain-hindbrain region.
TS20: cerebellum primordium	Present	Regionally restricted	5a	Dorsal expression in cerebellar anlage.

5a' ©

Specimen 5a': embryonic day 12.5; En1^tm2(cre)Wrst/En1⁺, Fgfr2^tm1Wrst/Fgfr2^tm1Wrst (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: cerebellum primordium	Present	Regionally restricted	5a'	Expression unchanged compared to control.
TS20: hindbrain	Present	Regionally restricted	5a'	Expression unchanged compared to control.
TS20: midbrain	Present	Regionally restricted	5a'	Expression unchanged compared to control.
TS20: midbrain-hindbrain junction	Present	Regionally restricted	5a'	Expression unchanged compared to control.

5g ©

Specimen 5g: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: hindbrain	Present	Regionally restricted	5g
TS20: midbrain	Present	Regionally restricted	5g

5g' ©

Specimen 5g': embryonic day 12.5; Fgfr3^tm1Dor/Fgfr3^tm1Dor (more

)

Structure	Level	Pattern	Image	Note
TS20: hindbrain	Present	Regionally restricted	5g'	Expression unchanged compared to control.
TS20: midbrain	Present	Regionally restricted	5g'	Expression unchanged compared to control.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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