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Gene Expression Data
Assay Details
Assay
Reference: J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type: RNA in situ
MGI Accession ID: MGI:6363703
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Islet1 probe7
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 3Ae: embryonic day 12.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS20: cranial nerve Present Regionally restricted 3Ae Expression in motor neurons of cranial nerve nuclei developing in the midbrain-hindbrain region (future 3rd and 4th cranial nerves).

Specimen 3Ae': embryonic day 12.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: cranial nerve Present Regionally restricted 3Ae' Motor neurons of cranial nerve nuclei located in same postion as in control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory