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Gene Expression Data
Assay Details
Assay
Reference: J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type: RNA in situ
MGI Accession ID: MGI:6363689
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Probe: Otx2 probe43
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 2Ac: embryonic day 10.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS17: midbrain Present 2Ac Expression in midbrain up to the midbrain-hindbrain boundary.
Specimen 2Ac': embryonic day 10.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: midbrain Present 2Ac' Expression unchanged compared to control.
Specimen 2Ad: embryonic day 12.5; Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Structure Level Pattern Image Note
TS20: midbrain Present 2Ad Expression in midbrain up to the midbrain-hindbrain boundary.
Specimen 2Ad': embryonic day 12.5; En1tm2(cre)Wrst/En1+, Fgfr2tm1Wrst/Fgfr2tm1Wrst (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: midbrain Present 2Ad' Expression unchanged compared to control.
Specimen 4Ab: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 4Ab
Specimen 4Ab': embryonic day 12.5; Fgfr3tm1Dor/Fgfr3tm1Dor (more )
Structure Level Pattern Image Note
TS20: midbrain-hindbrain junction Present 4Ab' Expression unchanged compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory