Fgfr2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:118802 Blak AA, et al., Fgfr2 and Fgfr3 are not required for patterning and maintenance of the midbrain and anterior hindbrain. Dev Biol. 2007 Mar 1;303(1):231-43
Assay type:	RNA in situ
MGI Accession ID:	MGI:6363684
Gene symbol:	Fgfr2
Gene name:	fibroblast growth factor receptor 2

Results

1Ba ©

Specimen 1Ba: embryonic day 9.0; Fgfr2^tm1Wrst/Fgfr2^tm1Wrst (more

)

Structure	Level	Pattern	Image	Note
TS14: future hindbrain	Present	Widespread	1Ba	Expression throughout midbrain-hindbrain region. Authors report that the introduced loxP sites do not appear to interfere with expression.
TS14: future midbrain	Present	Widespread	1Ba	Expression throughout midbrain-hindbrain region. Authors report that the introduced loxP sites do not appear to interfere with expression.

Specimen not shown: embryonic day 8.5; En1^tm2(cre)Wrst/En1⁺, Fgfr2^tm1Wrst/Fgfr2^tm1Wrst (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS13: future midbrain	Weak			Reduction of expression already observed at the 8-somite stage.
TS13: rhombomere 1	Weak			Reduction of expression already observed at the 8-somite stage.

1Bc ©

1Bd ©

Specimen 1Bc/d: embryonic day 9.0; En1^tm2(cre)Wrst/En1⁺, Fgfr2^tm1Wrst/Fgfr2^tm1Wrst (more

)
Note: Conditional mutant. False color overlay; red - Fgfr2; green - En1 reporter (assay MGI:7484557).

Structure	Level	Pattern	Image	Note
TS14: future midbrain	Absent		1Bd , 1Bc	Expression lost specifically in the midbrain-hindbrain region.
TS14: rhombomere 1	Absent		1Bd , 1Bc	Expression lost specifically in the midbrain-hindbrain region.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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