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Gene Expression Data
Assay Details
Assay
Reference: J:276706 Meguro F, et al., Bmp signaling in molar cusp formation. Gene Expr Patterns. 2019 Jun;32:67-71
Assay type: RNA in situ
MGI Accession ID: MGI:6361932
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Results
Specimen 3B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar Present Regionally restricted 3B Expression in a line, broader than that of Bmp2.
TS22: lower jaw mesenchyme Present Regionally restricted 3B Expression in mesenchyme buccal to tooth epithelium.

Specimen 3E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar Strong Regionally restricted 3E Strong expression in presumptive L2, L3, B2 and B3 cusp regions. Only weak expression in anterior region.

Specimen 3H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lower jaw molar Present Widespread 3H Expression in all presumptive cusp regions.

Specimen 3K: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: upper jaw molar Present Regionally restricted 3K Expression in cusp B2, B3, L2 and L3 regions. No expression in L1 and B1 regions.

Specimen 3N: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: upper jaw molar Present Regionally restricted 3N Linear expression, broader than that of Bmp2, with expression lacking in the center of the domain. Expression in posterior extended tooth germ.
TS22: upper jaw mesenchyme Present Regionally restricted 3N Expression in mesenchyme buccal to tooth epithelium.

Specimen 3Q: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: upper jaw molar Present Regionally restricted 3Q Two large domains of expression in first molars. No expression in center of posterior expression domain.

Specimen 3T: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: upper jaw molar Present Regionally restricted 3T Expression detected in all presumptive cusp regions, in characteristic V-shaped pattern.

Specimen 3W: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: upper jaw molar Present Regionally restricted 3W Expression in all cusp regions and transverse crest, in characteristic V-shaped pattern.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory