Gene Expression Data
Assay Details
Assay
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Reference:
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J:215297
Voronov D, et al., Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration. Invest Ophthalmol Vis Sci. 2013 May;54(5):3115-25
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6361768
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Gene symbol:
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Runx1
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Gene name:
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runt related transcription factor 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2A:
embryonic day 17.5; Runx1tm1Medv/Runx1 +
(more )
Specimen
2A:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Specimen
2B:
embryonic day 17.5; Runx1tm1Medv/Runx1 +
(more )
Specimen
2B:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Specimen
2C:
embryonic day 17.5; Runx1tm1Medv/Runx1 +
(more )
Specimen
2C:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Specimen
2D:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: meibomian gland |
Present |
Regionally restricted |
2D
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Expressed in ductal and mesenchymal components.
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TS28: eyelash |
Present |
Regionally restricted |
2D
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Expressed in the follicle bulge region.
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Specimen
2E:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: meibomian gland |
Present |
Regionally restricted |
2E
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Expressed in ductal and mesenchymal components.
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TS28: eyelash |
Present |
Regionally restricted |
2E
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Expressed in the follicle bulge region.
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Specimen
2F:
embryonic day 12.5; Runx1tm1Medv/Runx1 +
(more )
Specimen
2F:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Specimen
2G:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: lacrimal gland epithelium |
Strong |
Regionally restricted |
2G
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2H:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: lacrimal gland epithelium |
Strong |
Regionally restricted |
2H
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2I:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Strong |
Regionally restricted |
2I
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2J:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal day 17
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Strong |
Regionally restricted |
2J
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2K:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Strong |
Regionally restricted |
2K
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2L:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Strong |
Regionally restricted |
2L
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Expressed in ductal epithelium in a subset of cells within the acini called centroacinar cells.
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Specimen
2M:
postnatal month 6; Runx1tm1Medv/Runx1 +
(more )
Note: Also stained by PAS.
Specimen
2M:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Also stained by PAS.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Present |
Regionally restricted |
2M
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Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.
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Specimen
2N:
postnatal month 6; Runx1tm1Medv/Runx1 +
(more )
Note: Also stained by PAS.
Specimen
2N:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Note:
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Also stained by PAS.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Present |
Regionally restricted |
2N
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Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.
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Specimen
2O:
postnatal month 6; Runx1tm1Medv/Runx1 +
(more )
Note: Also stained by PAS.
Specimen
2O:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
|
postnatal month 6
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Sex:
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Not Specified
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Type:
|
section from whole mount
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Fixation:
|
Paraformaldehyde
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Embedding:
|
Paraffin
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Note:
|
Also stained by PAS.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: lacrimal gland epithelium |
Present |
Regionally restricted |
2O
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Expressed in all PAS+ ducts and centroacinar cells and some PAS- acinar cells.
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Specimen
not shown:
postnatal month 6; Runx1tm1Medv/Runx1 +
(more )
Specimen
not shown:
(close )
Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Runx1tm1Medv/Runx1+
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Age:
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postnatal month 6
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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